Biomolecules Folding and Disease

Proteomes, Interactomes and Biological Networks (85306) is 62-hour course of the 3^rd year of the Degree in Genomics taught by Emidio Capriotti. The course is running from November 4th to December 14th, 2021 in rooms and labs located in via della Beverara 123. The lectures can be also attended online through the URL http://bit.do/pibn-lectures. The Colab pages of the course are available at http://bit.do/pibn-colab. This page will include all the slides and materials of the course.

• Materials
  

  Course Schedule and General Information
  Protein Sequence and Structure	4, 5 and 9 November, 2021.
  Amino Acid Properties	11 November, 2021.
  Analysis and Prediction of Protein Complexes	16 November, 2021.
  Protein Interactions	17, 22 and 23 November, 2021.
  Introduction to Graph Theory	24 and 26 November, 2021.
  Motifs, Modules and Pathways	30 November, 1 and 2 December, 2021.
  Introduction to the Project	6 December, 2021.
  Project Implementation	7, 9 and 13 December, 2021.
  Project Report	14 December, 2021.




• Requirements
  

This is a theoretical and hands-on module which requires the use of PC. Students are encouraged to use their own laptop. Practical session of the course will be performed on a Linux OS.




• References
  

Dill and Chan. (1997) From Levinthal to pathways to funnels. Nature Structural Biology, 4:10–19.

Reichmann et al. (2007). The molecular architecture of protein–protein binding sites. Current Opinion in Structural Biology, 17:67–76

Shoemaker BA, Panchenko AR (2007). Deciphering protein-protein interactions. Part I. Experimental techniques and databases. PLoS Comput Biol. 3:e42.

Shoemaker BA, Panchenko AR (2007). Deciphering protein-protein interactions. Part II. Computational methods to predict protein and domain interaction partners. PLoS Comput Biol. 3:e43

Alon U. (2007). Network motifs: theory and experimental approaches. Nat Rev Genet. 8:450-461




• Evaluation
  

In this page we included the evaluation form anonymously compiled by the participants to evaluate the quality of our course. Answers submitted with numbers from 1 (No) to 4 (Yes) have been included in the following statistics calculated by R. The evaluation form was compiled by 19 participants which rated the course with an average score of 3.55 over 4 (88.9%). Data




• Previous Editions
  

November 2020:	The course Proteomes, Interactomes and Biological Networks was held from 2 November to 11 December, 2020. More information is available at this link.
November 2019:	The course Proteomes, Interactomes and Biological Networks was held from 5 November to 11 December, 2019. More information is available at this link.